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Zenit Science offers
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All assays are optimized to fit microtiter formats, requiring only low amounts (0.1 ml) of your precious samples material.
When choosing our standard package solutions prices are readily visible in the ordering system.
We ensure a rapid turnaround to faciliate efficient identification of promising leads early in drug development – One week following compound delivery.
Cost-effective standard packages can be directly ordered using our online system. We also offer tailoring of assays according to specific customer needs.
Antimicrobial Efficacy Assays
Standard assays
Assessment of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of your sample against a panel of bacterial strains (consisting of E. coli, S. aureus, P. aeruginosa, K. pneumoniae).
Assessment of the kinetics of bactericidal activity (time-kill) against either Escherichia coli or Staphylococcus aureus. Survival is measured after 0, 0.5, 2, 5 and 24 hours.
Colistin is included as internal control in the assays, and all samples are run in triplicate to ensure reliability and statistical power.
Exon-skipping analysis
Exon skipping (ES) is the most common alternative splicing event resulting in the loss of an exon. ES leads to a variety of human diseases and targeting ES events is an attractive therapeutic strategy.
If you are designing drugs targeting ES events, our ES analysis will confirm the specificity and evaluate the efficacy of your therapeutic strategy, assisting the further you in drug design and development.
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Assessment of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of your sample against a panel of bacterial strains (consisting of E. coli, S. aureus, P. aeruginosa, K. pneumoniae).